Sulfo-Cyanine5.5isawatersolublecyaninedyeforfarred/NIRapplicationssuchasinvivoimaging.Thedyepossessesfoursulfonategroupsthatrenderithighlyhydrophilicandwatersoluble.Aswellasothercyanines,sulfo-Cyanine5.5hasanoutstandingextinctioncoefficientthatmakesitabrightfluorescentlabelforthefarredregion.
Thisisanamine-containingfluorescentdye.Theaminegroupisseparatedfromthefluorophorebyarelativelylonglinkerthatfacilitatesconjugation.Thealiphaticprimaryaminegroupcanbecoupledwithvariouselectrophiles(activatedesters,epoxides,etc),andalsobeusedinenzymatictransaminationlabeling.
Appearance: | darkbluesolid |
Molecularweight: | 1077.41 |
Molecularformula: | C46H54K2N4O13S4 |
IUPACname: | (E)-4-[(2E,4E)-5-{5-[6-(6-Aminohexylamino)-6-oxohexyl]-3,3-dimethyl-10,12-bis(oxysulfonyl)-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentADIenylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonicaciddipotassiumsalt |
Solubility: | goodinwater,DMF,DMSO |
Qualitycontrol: | NMR1H,HPLC-MS(95%) |
Storageconditions: | Storage:24monthsafterreceivalat-20°Cinthedark.Transportation:atroomtemperatureforupto3weeks.Avoidprolongedexposuretolight.Desiccate. |
Excitationmaximum,nm: | 673 |
ε,L⋅mol−1⋅cm−1: | 195000 |
Emissionmaximum,nm: | 691 |
CF260: | 0.09 |
CF280: | 0.11 |
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